Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.51 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712396 | 0.84 | ALDH1A1 (0.47) | SYKIDO1NOS1ALDH1A1MAPT | |
| SCHEMBL10019236 | 0.82 | ALDH1A1 (0.46) | SYKIDO1NOS1ALDH1A1MAPT | |
| SCHEMBL10019234 | 0.82 | ALDH1A1 (0.50) | IDO1NOS1ALDH1A1MAPTKMT2A | |
| SCHEMBL6972024 | 0.82 | MAPT (0.46) | SYKIDO1NOS1ALDH1A1MAPT | |
| SCHEMBL14661726 | 0.82 | MAPT (0.40) | SYKZAP70IDO1NOS1CDK1 | |
| SCHEMBL11115631 | 0.81 | ALDH1A1 (0.59) | IDO1NOS1ALDH1A1MAPTKMT2A | |
| SCHEMBL28280216 | 0.80 | ZAP70 (0.45) | SYKZAP70CDK1PRKCAALDH1A1 | |
| SCHEMBL11114890 | 0.79 | ALDH1A1 (0.47) | IDO1NOS1ALDH1A1MAPTKMT2A | |
| SCHEMBL14155105 | 0.79 | TLR8 (0.47) | IDO1NOS1ALDH1A1MAPTKMT2A | |
| SCHEMBL13737973 | 0.79 | ALDH1A1 (0.47) | SYKIDO1NOS1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850192-A | Process for preparing 3,4-dihydroquinazoline derivatives | 南京正大天晴制药有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-115850192-A | Process for preparing 3,4-dihydroquinazoline derivatives | 南京正大天晴制药有限公司 | 2023-03-28 | — | — | CN | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |