Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14155105 | 0.90 | TLR8 (0.47) | MAPTALDH1A1ICMTPDK1PDK2 | |
| SCHEMBL28133362 | 0.88 | ABL1 (0.44) | MAPTALDH1A1ICMTPDK1PDK2 | |
| SCHEMBL3476587 | 0.87 | ABL1 (0.47) | MAPTALDH1A1ICMTPDK1PDK2 | |
| SCHEMBL3671419 | 0.85 | GABRG2 (0.50) | MAPTALDH1A1PDK1PDK2PDK3 | |
| SCHEMBL18707796 | 0.84 | MAPT (0.46) | MAPTALDH1A1IDO1MEN1KMT2A | |
| SCHEMBL5712396 | 0.84 | ALDH1A1 (0.47) | MAPTALDH1A1ICMTPDK1PDK2 | |
| SCHEMBL10019234 | 0.82 | ALDH1A1 (0.50) | MAPTALDH1A1ICMTPDK1PDK2 | |
| SCHEMBL10019236 | 0.82 | ALDH1A1 (0.46) | MAPTALDH1A1ICMTPDK1PDK2 | |
| SCHEMBL9850362 | 0.82 | SYK (0.51) | MAPTALDH1A1ICMTPDK1PDK2 | |
| SCHEMBL5540239 | 0.82 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147313-A1 | HOLE TRANSPORTING MATERIAL | 日本精化株式会社 | 2024-07-11 | — | — | WO | disclosed |
| US-20230257415-A1 | COMPOUNDS FOR TREATING CNS DISORDERS | SAGE THERAPEUTICS, INC. | 2023-08-17 | — | — | US | disclosed |
| US-7868204-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| US-7868205-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| US-7838520-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2010-11-23 | — | — | US | disclosed |
| US-7595343-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2009-09-29 | — | — | US | disclosed |
| US-20080132459-A1 | Inhibitors of Histone Deacetylase | METHYLGENE, INC. (CA) | 2008-06-05 | — | — | US | disclosed |
| US-20030166694-A1 | Glycinamides | MERCK PATENT GMBH (DE) | 2003-09-04 | — | — | US | disclosed |
| EP-1284961-A1 | GLYCINAMIDES | MERCK PATENT GmbH (DE) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092219-A1 | GLYCINAMIDES | MERCK PATENT GMBH (DE) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132459-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC5, HDAC3 | MAPT 2110/4885ALDH1A1 796/4885ICMT 4360/4885 |
| US-20230257415-A1 | COMPOUNDS FOR TREATING CNS DISORDERS | PMP22, SLC18A2, SLC6A1 | MAPT 48/4885ALDH1A1 1007/4885ICMT 3732/4885 |
| US-20030166694-A1 | Glycinamides | F11, SERPINC1, F13A1 | MAPT 4813/4885ALDH1A1 540/4885ICMT 3487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.