Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.34 |
| ▸ | PPARG | P37231 | 7/20 | 0.34 |
| ▸ | PPARD | Q03181 | 7/20 | 0.34 |
| ▸ | PPARA | Q07869 | 7/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850376 | 1.00 | CES2 (0.36) | CES2KMT2AMAPTGPR84PPARG | |
| SCHEMBL5669218 | 0.86 | CES2 (0.45) | CES2KMT2AMAPTGPR84PPARG | |
| SCHEMBL933572 | 0.86 | CES2 (0.45) | CES2KMT2AMAPTGPR84PPARG | |
| SCHEMBL4555960 | 0.78 | AKR1B1 (0.39) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL28407367 | 0.77 | CES2 (0.41) | CES2KMT2AGPR84PPARGPPARD | |
| SCHEMBL29151164 | 0.76 | NAAA (0.42) | KMT2AMAPTTSHRALDH1A1MEN1 | |
| SCHEMBL11173653 | 0.74 | CES2 (0.45) | CES2KMT2AMAPTGPR84PPARG | |
| SCHEMBL28384093 | 0.74 | CES2 (0.45) | CES2KMT2AMAPTGPR84PPARG | |
| SCHEMBL1043350 | 0.74 | CES2 (0.45) | CES2KMT2AMAPTGPR84PPARG | |
| SCHEMBL11859866 | 0.74 | CES2 (0.45) | CES2KMT2AMAPTGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057543-A | Storage stable mixture with dialkyl tin-sulfur polymerization catalyst; for reaction injection molding of polyurethanes | THE DOW CHEMICAL COMPANY (US) | 1991-10-15 | — | — | US | disclosed |
| EP-0415284-A2 | Blends of alkylene glycols and relatively high equivalent weight active hydrogen compounds containing additives and process for preparing thesame | THE DOW CHEMICAL COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |