Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | STK10 | O94804 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850403 | 0.90 | MEN1 (0.57) | MEN1KMT2AALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL9850493 | 0.83 | MEN1 (0.52) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL9850488 | 0.82 | MAPT (0.54) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL522650 | 0.81 | MEN1 (0.59) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL17754983 | 0.81 | MEN1 (0.62) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL9850257 | 0.81 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL17755176 | 0.80 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL9850386 | 0.80 | MEN1 (0.64) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL9850473 | 0.79 | CHRM2 (0.59) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL9850448 | 0.79 | ADRA1A (0.53) | MEN1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |