Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | NSD2 | O96028 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | COMT | P21964 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | APAF1 | O14727 | 2/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9850493 | 0.86 | MEN1 (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL522650 | 0.84 | MEN1 (0.59) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL9850257 | 0.84 | MEN1 (0.51) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL9850488 | 0.83 | MAPT (0.54) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9850592 | 0.82 | BCHE (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL9850416 | 0.80 | MEN1 (0.59) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL9850583 | 0.80 | MEN1 (0.51) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL9850394 | 0.80 | SLC40A1 (0.55) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL9850383 | 0.79 | KMT2A (0.46) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL9850499 | 0.79 | HTR1A (0.64) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |