Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 5/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507732 | 0.83 | CES1 (0.50) | SRCCES1PGRADRA2AADRA2B | |
| SCHEMBL1645556 | 0.82 | CES1 (0.48) | SRCCES1PGRADRA2AADRA2B | |
| SCHEMBL3349910 | 0.81 | CES1 (0.44) | SRCCES1PGRADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL16235168 | 0.79 | LMNA (0.44) | CES1HTR2ATDP1MAPTTSHR | |
| SCHEMBL28358545 | 0.79 | CES1 (0.50) | SRCCES1PGRADRA2AADRA2B | |
| SCHEMBL10384793 | 0.78 | CYP1A2 (0.42) | SRCCES1PGRADRA2AADRA2B | |
| SCHEMBL10493250 | 0.76 | CYP1A2 (0.48) | SRCCES1KCNH2MLYCDTDP1 | |
| Hydrochloric Acid SCHEMBL16235126 | 0.75 | GSK3B (0.53) | MLYCDMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6699073 | 0.75 | CES1 (0.50) | SRCCES1PGRADRA2AADRA2B | |
| SCHEMBL8463346 | 0.75 | CES1 (0.50) | SRCCES1PGRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423524-A2 | Propiophenone derivatives and their preparation and pharmaceutical use | MARUHO Co., Ltd. (JP) | 1991-04-24 | — | — | EP | disclosed |