Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201888 | 0.88 | HTT (0.60) | LMNAHSD17B10HTTRAB9AATM | |
| SCHEMBL1788851 | 0.76 | LMNA (0.67) | LMNAHSD17B10CRHBPCRHR2ATM | |
| SCHEMBL4494122 | 0.76 | EPHX1 (0.58) | HTTRAB9AATMNPC1MAPT | |
| SCHEMBL6904222 | 0.76 | EPHX1 (0.58) | HTTRAB9AATMNPC1MAPT | |
| SCHEMBL2554178 | 0.76 | HTR2A (0.57) | HTTRAB9AATMNPC1MAPT | |
| SCHEMBL9850542 | 0.75 | HTT (0.53) | LMNAHTTRAB9AATMNPC1 | |
| SCHEMBL13798282 | 0.75 | LMNA (0.55) | LMNAHSD17B10HTTRAB9AATM | |
| Hydrochloric Acid SCHEMBL9850640 | 0.74 | SMN1; SMN2 (0.78) | LMNAHSD17B10HTTRAB9AATM | |
| Hydrochloric Acid SCHEMBL9850694 | 0.73 | SMN1; SMN2 (0.76) | LMNAHSD17B10HTTRAB9AATM | |
| Dimethylamine SCHEMBL7287513 | 0.73 | LMNA (0.61) | LMNAHSD17B10CRHBPCRHR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423524-A2 | Propiophenone derivatives and their preparation and pharmaceutical use | MARUHO Co., Ltd. (JP) | 1991-04-24 | — | — | EP | disclosed |