Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081748 | 1.00 | SOAT1 (0.47) | SOAT1NPC1RECQLRAB9ACYP3A4 | |
| SCHEMBL9850717 | 1.00 | SOAT1 (0.47) | SOAT1NPC1RECQLRAB9ACYP3A4 | |
| SCHEMBL6937171 | 0.98 | SOAT1 (0.44) | SOAT1NPC1RECQLRAB9ACYP3A4 | |
| SCHEMBL6936975 | 0.93 | NPC1 (0.48) | SOAT1NPC1RECQLRAB9ACYP3A4 | |
| SCHEMBL6939611 | 0.87 | CHRNB2 (0.42) | NPC1RECQLRAB9ASLC5A2CHRNB2 | |
| SCHEMBL4273729 | 0.80 | RAB9A (0.56) | SOAT1NPC1RECQLRAB9ACYP3A4 | |
| SCHEMBL18034939 | 0.80 | NPC1 (0.50) | SOAT1NPC1RECQLRAB9ACYP3A4 | |
| SCHEMBL2492398 | 0.79 | HTT (0.45) | NPC1CHRNB2CHRNA4MEN1MAPT | |
| SCHEMBL12204710 | 0.79 | SOAT1 (0.47) | SOAT1NPC1RECQLRAB9ACYP3A4 | |
| SCHEMBL10894021 | 0.78 | CHRNB2 (0.41) | NPC1RECQLRAB9ACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409634-A2 | Liquid crystal compounds and optically active compounds | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |