Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850823 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9AL3MBTL1NPC1NFKB1 | |
| SCHEMBL9850625 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9AL3MBTL1NPC1NFKB1 | |
| SCHEMBL8452862 | 0.85 | PTPN11 (0.52) | SMN1; SMN2L3MBTL1S1PR1S1PR3S1PR4 | |
| SCHEMBL7788809 | 0.85 | PTPN11 (0.52) | SMN1; SMN2L3MBTL1S1PR1S1PR3S1PR4 | |
| SCHEMBL6534928 | 0.85 | NPC1 (0.49) | SMN1; SMN2RAB9AL3MBTL1NPC1S1PR1 | |
| SCHEMBL9806818 | 0.85 | RAB9A (0.47) | SMN1; SMN2RAB9AL3MBTL1NPC1NFKB1 | |
| SCHEMBL9806767 | 0.84 | RAB9A (0.57) | SMN1; SMN2RAB9AL3MBTL1NPC1NFKB1 | |
| SCHEMBL9806797 | 0.84 | RAB9A (0.56) | SMN1; SMN2RAB9AL3MBTL1NPC1NFKB1 | |
| SCHEMBL9192073 | 0.84 | RAB9A (0.57) | SMN1; SMN2RAB9AL3MBTL1NPC1NFKB1 | |
| SCHEMBL9806816 | 0.84 | RAB9A (0.57) | SMN1; SMN2RAB9AL3MBTL1NPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409634-A2 | Liquid crystal compounds and optically active compounds | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |