Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16984371 | 0.75 | CYP2C9 (0.44) | CYP2D6CYP2C9HIF1APTPN5TYR | |
| SCHEMBL3114470 | 0.75 | HDAC3 (0.45) | HIF1AALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL16984373 | 0.74 | CYP2C9 (0.42) | CYP2D6CYP2C9HIF1APTPN5TYR | |
| SCHEMBL8916291 | 0.73 | KIF11 (0.42) | CYP2C9PTPN5ACEMAPTSMN1; SMN2 | |
| SCHEMBL9850911 | 0.73 | TYR (0.45) | CYP2D6CYP2C9HIF1APTPN5TYR | |
| SCHEMBL12205460 | 0.72 | CYP2C9 (0.50) | CYP2D6CYP2C9HIF1APTPN5TYR | |
| SCHEMBL16984370 | 0.71 | CYP2D6 (0.40) | CYP2D6CYP2C9HIF1APTPN5TYR | |
| SCHEMBL548066 | 0.69 | TSHR (0.50) | CYP2D6CYP2C9HIF1APTPN5TYR | |
| SCHEMBL6281512 | 0.69 | CYP2C9 (0.50) | CYP2D6CYP2C9HIF1APTPN5TYR | |
| SCHEMBL16191360 | 0.69 | CYP2C9 (0.50) | CYP2D6CYP2C9HIF1APTPN5TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043372-A | Light stabilizers for polyolefins; reacting hydrazine with bis(half ester-half amide) | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0434079-A1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |