Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3114470 | 0.88 | HDAC3 (0.45) | MAPTKDM4EKMT2AHDAC3HDAC4 | |
| SCHEMBL18812907 | 0.75 | KIF11 (0.48) | KIF11CYP2C9PTPN5ADAMTS4ADAMTS5 | |
| SCHEMBL159573 | 0.74 | KIF11 (0.46) | KIF11CYP2C9PTPN5MAPTSMN1; SMN2 | |
| SCHEMBL8916294 | 0.73 | KIF11 (0.42) | KIF11CYP2C9PTPN5ADAMTS4ADAMTS5 | |
| SCHEMBL9850906 | 0.73 | CYP2D6 (0.43) | KIF11CYP2C9PTPN5MAPTSMN1; SMN2 | |
| SCHEMBL2362106 | 0.73 | ADAMTS4 (0.51) | KIF11CYP2C9PTPN5ADAMTS4ADAMTS5 | |
| SCHEMBL1549012 | 0.71 | HDAC3 (0.45) | MAPTKDM4EKMT2AHDAC3HDAC4 | |
| SCHEMBL10806930 | 0.70 | KIF11 (0.52) | KIF11CYP2C9PTPN5MAPTSMN1; SMN2 | |
| SCHEMBL3421942 | 0.69 | KIF11 (0.59) | KIF11CYP2C9PTPN5NPC1RAB9A | |
| SCHEMBL15832876 | 0.69 | ALDH1A1 (0.58) | KIF11CYP2C9PTPN5CYP1A2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633364-A | N4 -substituted 2'-deoxycytidine compounds, oligonucleotides including N4 -labeled 2'-deoxycytidines, and a process for making oligonucleotides with N-modified 2'-deoxycytidines | AMOCO CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5405950-A | N4 -substituted cytidines and process for incorporation into an oligonucleotides | AMOCO CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |