Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.67 |
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21010901 | 0.88 | ESR1 (0.52) | ALOX5KEAP1MEN1KMT2AMAPT | |
| SCHEMBL11764362 | 0.82 | ALOX5 (0.74) | ALOX5BCL2BCL2L1HSD17B3KEAP1 | |
| SCHEMBL27743753 | 0.81 | ALOX5 (0.67) | ALOX5BCL2BCL2L1HSD17B3KEAP1 | |
| SCHEMBL29655583 | 0.80 | ALOX5 (1.00) | ALOX5BCL2BCL2L1HSD17B3KEAP1 | |
| SCHEMBL29655585 | 0.80 | ALOX5 (1.00) | ALOX5BCL2BCL2L1HSD17B3KEAP1 | |
| SCHEMBL1514183 | 0.80 | HTR2A (0.48) | ALOX5BCL2BCL2L1MAPTCYP3A4 | |
| SCHEMBL68292 | 0.80 | ALOX5 (1.00) | ALOX5BCL2BCL2L1HSD17B3KEAP1 | |
| SCHEMBL6292267 | 0.80 | ALOX5 (0.71) | ALOX5BCL2BCL2L1HSD17B3KEAP1 | |
| SCHEMBL9656059 | 0.77 | CYP3A4 (0.58) | ALOX5BCL2BCL2L1MEN1KMT2A | |
| SCHEMBL810597 | 0.77 | HDAC6 (0.47) | ALOX5BCL2BCL2L1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107973727-A | Between disubstituted benzenes phenolic compounds and preparation method thereof and anti-tubercle bacillus application | 中山大学 | 2018-05-01 | — | — | CN | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |