Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | BCL2 | P10415 | 1/20 | 0.63 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | TYR | P14679 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29655585 | 1.00 | ALOX5 (1.00) | ALOX5MEN1KMT2AMAPTBCL2 | |
| SCHEMBL29655583 | 1.00 | ALOX5 (1.00) | ALOX5MEN1KMT2AMAPTBCL2 | |
| SCHEMBL7692955 | 0.89 | MEN1 (0.87) | ALOX5MEN1KMT2AMAPTBCL2 | |
| SCHEMBL4055779 | 0.89 | MAPT (0.81) | ALOX5MEN1KMT2AMAPTKEAP1 | |
| SCHEMBL8519994 | 0.88 | ALOX5 (0.77) | ALOX5MEN1KMT2AMAPTBCL2 | |
| SCHEMBL278523 | 0.87 | MAPT (0.78) | ALOX5MEN1KMT2AMAPTKEAP1 | |
| SCHEMBL6916752 | 0.87 | ALOX5 (0.75) | ALOX5MEN1KMT2AMAPTBCL2 | |
| SCHEMBL11764362 | 0.85 | ALOX5 (0.74) | ALOX5MEN1KMT2AMAPTBCL2 | |
| SCHEMBL6292352 | 0.84 | ALOX5 (0.72) | ALOX5MEN1KMT2AMAPTBCL2 | |
| SCHEMBL4056986 | 0.83 | MAPT (0.72) | ALOX5MEN1KMT2AMAPTKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 784 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329154-B2 | Compositions comprising a dispersant and microcapsules containing an active material | THE PROCTER & GAMBLE COMPANY (US) | 2012-12-11 | — | — | US | claimed |
| US-20090214606-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | CIBA SPECIALTY CHEMICALS CORP. | 2009-08-27 | — | — | US | claimed |
| US-7524966-B2 | Method for preparing ladderanes | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-04-28 | — | — | US | claimed |
| US-20090088572-A1 | METHOD FOR PREPARING LADDERANES | NATIONAL SCIENCE FOUNDATION | 2009-04-02 | — | — | US | claimed |
| EP-1879457-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | Ciba Specialty Chemicals Holding, Inc. (CH) | 2008-01-23 | — | — | EP | claimed |
| US-20070231295-A1 | Antimicrobial Silicon Oxide Flakes | CIBA SPECIALTY CHEMICALS CORP. | 2007-10-04 | — | — | US | claimed |
| WO-2007089785-A2 | APPARATUS AND SEMICONDUCTOR CO-CRYSTAL | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-08-09 | — | — | WO | claimed |
| EP-1755381-A2 | ANTIMICROBIAL SILICON OXIDE FLAKES | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-02-28 | — | — | EP | claimed |
| US-20060258768-A1 | Compositions comprising a dispersant and microcapsules containing an active material | UCHIYAMA HIROTAKA | 2006-11-16 | — | — | US | claimed |
| WO-2006120135-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-11-16 | — | — | WO | claimed |
| WO-2005035473-A2 | METHOD FOR PREPARING LADDERANES FROM PRE-ORIENTED POLYENES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2005-04-21 | — | — | WO | claimed |
| US-20050049390-A1 | Phase transfer catalyzed method for preparation of polyetherimides | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | claimed |
| EP-1495102-A2 | COMPOSITIONS COMPRISING A DISPERSANT AND MICROCAPSULES CONTAINING AN ACTIVE MATERIAL | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-12 | — | — | EP | claimed |
| WO-2004024861-A1 | HARD SURFACE TREATING COMPOSITIONS | RECKITT BENCKISER INC (US) | 2004-03-25 | — | — | WO | claimed |
| US-20040044134-A1 | METHOD TO MAKE A SOLID POLYMERIC PHOSPHATE AND RESINOUS COMPOSITIONS CONTAINING IT | GENERAL ELECTRIC COMPANY | 2004-03-04 | — | — | US | claimed |
| US-20030216488-A1 | Compositions comprising a dispersant and microcapsules containing an active material | THE PROCTER & GAMBLE COMPANY | 2003-11-20 | — | — | US | claimed |
| WO-2003089561-A2 | COMPOSITIONS COMPRISING A DISPERSANT AND MICROCAPSULES CONTAINING AN ACTIVE MATERIAL | THE PROCTER & GAMBLE COMPANY (US) | 2003-10-30 | — | — | WO | claimed |
| US-5229243-A | Addition polymer core, polyurethane or polythiourethane shell | KAO CORPORATION (JP) | 1993-07-20 | — | — | US | claimed |
| EP-0243449-A1 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1987-11-04 | — | — | EP | claimed |
| WO-1987002367-A2 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1987-04-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070231295-A1 | Antimicrobial Silicon Oxide Flakes | SIK2, SIK3, SIK1 | ALOX5 853/4885MEN1 3335/4885KMT2A 2721/4885 |
| US-20090214606-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | ORAI3, PRF1, THPO | ALOX5 783/4885MEN1 1436/4885KMT2A 3677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.