Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679655 | 0.80 | KMT2A (0.54) | KMT2AMEN1SOAT2SOAT1ACAT1 | |
| SCHEMBL9680035 | 0.77 | KMT2A (0.43) | KMT2AMEN1SOAT2SOAT1ACAT1 | |
| SCHEMBL9851062 | 0.76 | SOAT2 (0.43) | KMT2AMEN1SOAT2SOAT1ACAT1 | |
| SCHEMBL9678692 | 0.76 | KMT2A (0.44) | KMT2AMEN1SOAT2SOAT1ACAT1 | |
| SCHEMBL9678916 | 0.74 | MEN1 (0.47) | KMT2AMEN1SOAT2SOAT1SMN1; SMN2 | |
| SCHEMBL9678933 | 0.73 | KMT2A (0.63) | KMT2AMEN1SOAT2SOAT1SMN1; SMN2 | |
| SCHEMBL9679362 | 0.73 | KMT2A (0.63) | KMT2AMEN1SOAT2SOAT1SMN1; SMN2 | |
| SCHEMBL9678585 | 0.73 | KMT2A (0.63) | KMT2AMEN1SOAT2SOAT1SMN1; SMN2 | |
| SCHEMBL9678591 | 0.73 | KMT2A (0.63) | KMT2AMEN1SOAT2SOAT1SMN1; SMN2 | |
| SCHEMBL9679385 | 0.70 | KMT2A (0.55) | KMT2AMEN1SOAT2SOAT1ACAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |