Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851386 | 0.94 | KMT2A (0.67) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL9851341 | 0.81 | ALDH1A1 (0.62) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL5579198 | 0.81 | KDM4E (0.85) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL4491778 | 0.77 | ALDH1A1 (0.61) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL9851357 | 0.76 | ALDH1A1 (0.60) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL5578267 | 0.74 | KDM4E (1.00) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL5988415 | 0.74 | ACHE (1.00) | ACHEAPPBCHE | |
| Hydrochloric Acid SCHEMBL5578263 | 0.73 | KDM4E (0.73) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL1110808 | 0.73 | ALDH1A1 (0.73) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL9851342 | 0.73 | KMT2A (0.62) | KMT2AKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | claimed |
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |