Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 6/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.41 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851387 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1GAAHPGDTSHR | |
| Palmitic Acid SCHEMBL8003937 | 0.76 | BCHE (0.64) | KDM4EALDH1A1TSHRLMNAHSD17B10 | |
| Tacrine SCHEMBL8000923 | 0.76 | BCHE (0.64) | KDM4EALDH1A1TSHRLMNAHSD17B10 | |
| Aminacrine SCHEMBL29597510 | 0.72 | ALDH1A1 (0.56) | KDM4EALDH1A1GAAHPGDTSHR | |
| Oleic Acid SCHEMBL8003926 | 0.71 | HSD17B10 (0.56) | KDM4EALDH1A1HPGDTSHRLMNA | |
| Oleic Acid SCHEMBL8003927 | 0.71 | HSD17B10 (0.56) | KDM4EALDH1A1HPGDTSHRLMNA | |
| SCHEMBL5045645 | 0.68 | KDM4E (0.66) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL11840628 | 0.68 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL18997605 | 0.67 | KRAS (0.41) | KDM4EALDH1A1TSHRLMNAMAPT | |
| SCHEMBL11832315 | 0.67 | P2RY12 (0.49) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | claimed |