Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 7/20 | 0.48 |
| ▸ | BCHE | P06276 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.48 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851381 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1LMNAHPGDGAA | |
| SCHEMBL9851341 | 0.73 | ALDH1A1 (0.62) | KDM4EALDH1A1LMNAHPGDGAA | |
| SCHEMBL5045645 | 0.72 | KDM4E (0.66) | KDM4EALDH1A1LMNAHPGDGAA | |
| SCHEMBL18997607 | 0.70 | KRAS (0.50) | KDM4EALDH1A1LMNATSHRMAPT | |
| SCHEMBL5047155 | 0.70 | KDM4E (0.68) | KDM4EALDH1A1LMNAHPGDGAA | |
| SCHEMBL4491778 | 0.69 | ALDH1A1 (0.61) | KDM4EALDH1A1LMNAHPGDGAA | |
| Hydrochloric Acid SCHEMBL9851357 | 0.68 | ALDH1A1 (0.60) | KDM4EALDH1A1LMNAHPGDGAA | |
| Tacrine SCHEMBL7998486 | 0.68 | ACHE (0.82) | KDM4EALDH1A1LMNATSHRHSD17B10 | |
| Tacrine SCHEMBL8003897 | 0.68 | ACHE (0.82) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL9550534 | 0.67 | BCHE (0.65) | KDM4EALDH1A1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | claimed |