Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | PLK4 | O00444 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.44 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22777733 | 0.71 | BCL2L1 (0.46) | BCL2L1PLK4AURKADAPK3CHEK2 | |
| SCHEMBL844336 | 0.70 | BCL2L1 (0.53) | BCL2L1ALDH1A1KDM4EMEN1GLA | |
| SCHEMBL27084096 | 0.69 | KDM4E (0.41) | BCL2L1PLK4AURKADAPK3CHEK2 | |
| SCHEMBL6836536 | 0.68 | ALDH1A1 (0.71) | BCL2L1PLK4AURKADAPK3CHEK2 | |
| SCHEMBL843921 | 0.68 | KDM4E (0.54) | CSNK2A1ALDH1A1KDM4EMEN1GLA | |
| Hydrochloric Acid SCHEMBL26117682 | 0.68 | KDM4E (0.40) | BCL2L1PLK4AURKADAPK3CHEK2 | |
| SCHEMBL2895870 | 0.68 | MAPT (0.68) | BCL2L1ALDH1A1KDM4EMEN1GLA | |
| SCHEMBL11740201 | 0.67 | ALDH1A1 (0.69) | BCL2L1PLK4AURKADAPK3CHEK2 | |
| SCHEMBL7461107 | 0.67 | KDM4E (0.68) | BCL2L1ALDH1A1KDM4EMEN1GLA | |
| SCHEMBL4947800 | 0.67 | SLC22A12 (0.40) | PLK4AURKADAPK3CHEK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416820-A2 | Novel compounds exhibiting a vasodilating activity and inhibitory activity for platelet aggregation and pharmaceutical compositions containing them | Hidaka, Hiroyoshi (JP) | 1991-03-13 | — | — | EP | disclosed |