Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10270731 | 0.86 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL3613094 | 0.79 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL3613088 | 0.79 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL21623729 | 0.77 | ALOX15 (0.46) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL21623759 | 0.77 | GSTP1 (0.44) | ALDH1A1L3MBTL1MAPTKMT2ATXNRD1 | |
| SCHEMBL21623731 | 0.77 | MEN1 (0.51) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| Trifluoroacetic Acid SCHEMBL3604898 | 0.76 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL4432761 | 0.76 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL10270729 | 0.75 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTKMT2ACA12 | |
| SCHEMBL21623768 | 0.74 | MDM2 (0.48) | ALDH1A1L3MBTL1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434038-A1 | Fused imidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-06-26 | — | — | EP | disclosed |