Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066899 | 0.80 | TXNRD1 (0.51) | TXNRD1MAPTTSHRTDP1ALDH1A1 | |
| SCHEMBL21801996 | 0.79 | TXNRD1 (0.50) | TXNRD1MAPTTSHRTDP1ALDH1A1 | |
| SCHEMBL17618250 | 0.78 | TXNRD1 (0.52) | TXNRD1MAPTTSHRTDP1ALDH1A1 | |
| SCHEMBL15472273 | 0.76 | MAPT (0.49) | TXNRD1MAPTTSHRTDP1ALDH1A1 | |
| SCHEMBL19171762 | 0.76 | TXNRD1 (0.48) | TXNRD1MAPTTDP1ALDH1A1HTT | |
| SCHEMBL801582 | 0.76 | CTSB (0.51) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL29391396 | 0.75 | TDP1 (0.45) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL671296 | 0.75 | TDP1 (0.45) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL27537939 | 0.74 | CTSB (0.50) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL23410594 | 0.73 | TXNRD1 (0.45) | TXNRD1MAPTTDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434038-A1 | Fused imidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-06-26 | — | — | EP | disclosed |