Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469151 | 0.88 | MAPT (0.89) | MAPTRAB9AL3MBTL1TDP1CA1 | |
| SCHEMBL5054312 | 0.86 | MAPT (0.85) | MAPTRAB9AL3MBTL1TDP1CA1 | |
| SCHEMBL4546171 | 0.86 | MAPT (0.59) | MAPTRAB9AL3MBTL1TDP1CA1 | |
| SCHEMBL1951546 | 0.86 | MAPT (1.00) | MAPTRAB9AL3MBTL1TDP1CA1 | |
| SCHEMBL12921583 | 0.85 | MAPT (0.77) | MAPTRAB9AL3MBTL1TDP1CA1 | |
| SCHEMBL7937774 | 0.84 | MAPT (0.82) | MAPTRAB9AL3MBTL1TDP1CA1 | |
| SCHEMBL522153 | 0.84 | L3MBTL1 (0.61) | MAPTL3MBTL1GAANPC1ALDH1A1 | |
| SCHEMBL20148862 | 0.84 | L3MBTL1 (0.79) | MAPTRAB9AL3MBTL1GAAKDM4E | |
| SCHEMBL12921588 | 0.83 | GAA (0.80) | MAPTRAB9AL3MBTL1TDP1CA1 | |
| SCHEMBL9851540 | 0.83 | TSHR (0.65) | L3MBTL1TDP1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428268-A2 | Pharmaceutical phenylpyridone derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-05-22 | — | — | EP | disclosed |