Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10646186 | 0.79 | KDM4E (0.33) | KDM4E | |
| SCHEMBL25922429 | 0.79 | DRD2 (0.30) | — | |
| SCHEMBL27798489 | 0.78 | GLB1 (0.39) | GBA1 | |
| SCHEMBL26381410 | 0.77 | — | — | |
| SCHEMBL9851577 | 0.76 | KDM4E (0.40) | KDM4E | |
| SCHEMBL24108242 | 0.73 | — | — | |
| SCHEMBL10639698 | 0.73 | — | — | |
| SCHEMBL4550233 | 0.72 | — | — | |
| SCHEMBL26381296 | 0.71 | — | — | |
| SCHEMBL18976756 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340599-A1 | AMPK ACTIVATORS | KALLYOPE, INC. | 2022-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220340599-A1 | AMPK ACTIVATORS | PRKAG1, PRKAG2, PRKAA1 | KDM4E 636/4885GBA1 2994/4885L3MBTL3 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.