Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18209382 | 0.70 | BACE1 (0.37) | OPRM1 | |
| SCHEMBL17113583 | 0.70 | HSD17B10 (0.34) | NEK2 | |
| SCHEMBL29444509 | 0.66 | OPRM1 (0.38) | OPRM1 | |
| SCHEMBL1383352 | 0.66 | OPRM1 (0.38) | OPRM1 | |
| SCHEMBL318419 | 0.65 | NEK2 (0.31) | NEK2 | |
| SCHEMBL758765 | 0.65 | NEK2 (0.35) | NEK2 | |
| SCHEMBL20954930 | 0.62 | OPRM1 (0.32) | OPRM1 | |
| SCHEMBL20955132 | 0.62 | OPRM1 (0.32) | OPRM1 | |
| SCHEMBL7400480 | 0.62 | NEK2 (0.32) | NEK2OPRM1 | |
| SCHEMBL2604297 | 0.62 | NEK2 (0.32) | NEK2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417631-A2 | Condensed diazepinones, process for their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1991-03-20 | — | — | EP | disclosed |