SCHEMBL9851716

SCHEMBL9851716

Oc1ncnc2c1ncn2[C@@H]1O[C@H](COCc2ccccc2)C[C@H]1O

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 4/20 0.48
AHCY P23526 2/20 0.46
NT5E P21589 1/20 0.45
BCHE P06276 1/20 0.44
PDE2A O00408 1/20 0.43
DOT1L Q8TEK3 1/20 0.42
ADORA2A P29274 3/20 0.42
ADORA1 P30542 1/20 0.42
TP53 P04637 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
STAT6 P42226 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9851725 1.00 SLC29A1 (0.48) SLC29A1AHCYNT5EBCHEPDE2A
SCHEMBL9851769 0.91 PDE2A (0.47) SLC29A1NT5EBCHEPDE2A
SCHEMBL9851780 0.91 PDE2A (0.47) SLC29A1NT5EBCHEPDE2A
SCHEMBL11402107 0.89 AHCY (0.58) AHCYNT5EBCHEPDE2ADOT1L
SCHEMBL9851786 0.88 ADORA2A (0.46) SLC29A1AHCYPDE2ADOT1LADORA2A
SCHEMBL9851892 0.84 SLC29A1 (0.41) SLC29A1AHCYPDE2ADOT1LADORA2A
SCHEMBL9851893 0.84 SLC29A1 (0.41) SLC29A1AHCYPDE2ADOT1LADORA2A
SCHEMBL1140717 0.83 SLC29A1 (0.64) SLC29A1AHCYPDE2AADORA2AADORA1
SCHEMBL9851706 0.82 SLC29A1 (0.44) SLC29A1AHCYNT5EBCHEDOT1L
SCHEMBL9851713 0.82 SLC29A1 (0.44) SLC29A1AHCYNT5EBCHEDOT1L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450102-A1 NUCLEOSIDE DERIVATIVE Yamasa Shoyu Kabushiki Kaisha (JP) 1991-10-09 EP claimed
EP-0450102-A1 NUCLEOSIDE DERIVATIVE Yamasa Shoyu Kabushiki Kaisha (JP) 1991-10-09 EP disclosed