SCHEMBL9851769

SCHEMBL9851769

Oc1ncnc2c1ncn2[C@@H]1O[C@H](COCc2ccc(Cl)cc2)C[C@H]1O

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 0.47
SLC29A1 Q99808 3/20 0.45
NT5E P21589 2/20 0.44
BCHE P06276 1/20 0.41
PRMT5 O14744 3/20 0.40
WDR77 Q9BQA1 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9851780 1.00 PDE2A (0.47) PDE2ASLC29A1NT5EBCHEPRMT5
SCHEMBL9851716 0.91 SLC29A1 (0.48) PDE2ASLC29A1NT5EBCHE
SCHEMBL9851725 0.91 SLC29A1 (0.48) PDE2ASLC29A1NT5EBCHE
SCHEMBL9851713 0.81 SLC29A1 (0.44) SLC29A1NT5EBCHE
SCHEMBL646509 0.81 BCHE (0.46) SLC29A1NT5EBCHE
SCHEMBL9851706 0.81 SLC29A1 (0.44) SLC29A1NT5EBCHE
SCHEMBL11402107 0.80 AHCY (0.58) PDE2ANT5EBCHE
SCHEMBL9851785 0.80 BCHE (0.45) SLC29A1NT5EBCHE
SCHEMBL9851797 0.80 BCHE (0.45) SLC29A1NT5EBCHE
SCHEMBL98800 0.80 SLC29A1 (0.56) SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450102-A1 NUCLEOSIDE DERIVATIVE Yamasa Shoyu Kabushiki Kaisha (JP) 1991-10-09 EP disclosed