SCHEMBL9851733

SCHEMBL9851733

C[Si](C)(C)O[C@@H]1C[C@@H](CO)O[C@H]1n1cnc2c(O)ncnc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 2/20 0.41
GAA P10253 1/20 0.41
PI4KA P42356 2/20 0.41
PI4K2B Q8TCG2 2/20 0.41
PI4K2A Q9BTU6 2/20 0.41
PI4KB Q9UBF8 2/20 0.41
ADORA1 P30542 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
ADORA3 P0DMS8 2/20 0.40
DPP4 P27487 1/20 0.40
MEN1 O00255 1/20 0.40
SLC28A1 O00337 1/20 0.40
MAP3K7 O43318 1/20 0.40
SLC28A2 O43868 1/20 0.40
GAPDH P04406 1/20 0.40
MAPK1 P28482 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA2B P29275 1/20 0.40
STAT6 P42226 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9851739 1.00 SLC29A1 (0.41) SLC29A1GAAPI4KAPI4K2BPI4K2A
SCHEMBL9851727 0.90 ADORA3 (0.37) GAAPI4KAPI4K2BPI4K2API4KB
SCHEMBL9851766 0.89 SLC29A1 (0.39) SLC29A1GAAPI4KAPI4K2BPI4K2A
SCHEMBL9851773 0.89 SLC29A1 (0.39) SLC29A1GAAPI4KAPI4K2BPI4K2A
SCHEMBL9851839 0.88 SLC29A1 (0.42) SLC29A1GAAPI4KAPI4K2BPI4K2A
SCHEMBL9851842 0.88 SLC29A1 (0.42) SLC29A1GAAPI4KAPI4K2BPI4K2A
SCHEMBL9851699 0.85 GAA (0.38) SLC29A1GAAPI4KAPI4K2BPI4K2A
SCHEMBL9851872 0.83 GAA (0.43) SLC29A1GAAPI4KAPI4K2BPI4K2A
SCHEMBL9851878 0.83 GAA (0.43) SLC29A1GAAPI4KAPI4K2BPI4K2A
SCHEMBL98800 0.82 SLC29A1 (0.56) SLC29A1PI4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450102-A1 NUCLEOSIDE DERIVATIVE Yamasa Shoyu Kabushiki Kaisha (JP) 1991-10-09 EP disclosed