SCHEMBL9851699

SCHEMBL9851699

CCCC(C)(C)[Si](C)(C)O[C@@H]1C[C@@H](CO)O[C@H]1n1cnc2c(O)ncnc21

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
SLC29A1 Q99808 2/20 0.37
AHCY P23526 1/20 0.36
PI4KA P42356 1/20 0.36
PI4K2B Q8TCG2 1/20 0.36
PI4K2A Q9BTU6 1/20 0.36
PI4KB Q9UBF8 1/20 0.36
ADORA1 P30542 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9851844 0.92 ADORA3 (0.35) GAAAHCYADORA1
SCHEMBL9851773 0.89 SLC29A1 (0.39) GAASLC29A1PI4KAPI4K2BPI4K2A
SCHEMBL9851766 0.89 SLC29A1 (0.39) GAASLC29A1PI4KAPI4K2BPI4K2A
SCHEMBL9851739 0.85 SLC29A1 (0.41) GAASLC29A1PI4KAPI4K2BPI4K2A
SCHEMBL9851733 0.85 SLC29A1 (0.41) GAASLC29A1PI4KAPI4K2BPI4K2A
SCHEMBL9851908 0.81 ADORA1 (0.35) GAAPI4KAPI4K2BPI4K2API4KB
SCHEMBL9851740 0.80 BCHE (0.41) SLC29A1AHCYADORA1
SCHEMBL9851878 0.80 GAA (0.43) GAASLC29A1AHCYPI4KAPI4K2B
SCHEMBL9851872 0.80 GAA (0.43) GAASLC29A1AHCYPI4KAPI4K2B
SCHEMBL9851842 0.80 SLC29A1 (0.42) GAASLC29A1PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450102-A1 NUCLEOSIDE DERIVATIVE Yamasa Shoyu Kabushiki Kaisha (JP) 1991-10-09 EP claimed
EP-0450102-A1 NUCLEOSIDE DERIVATIVE Yamasa Shoyu Kabushiki Kaisha (JP) 1991-10-09 EP disclosed