SCHEMBL9851742

SCHEMBL9851742

O=c1[nH]cnc2c1cnn2[C@@H]1O[C@H](CO)[C@@H](O[SiH3])[C@H]1O[SiH3]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
MAPT P10636 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ATG7 O95352 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
LMNA P02545 3/20 0.36
POLB P06746 1/20 0.36
ALB P02768 1/20 0.36
MAPK1 P28482 1/20 0.36
STING1 Q86WV6 1/20 0.36
P2RX3 P56373 1/20 0.33
HTT P42858 1/20 0.33
THRB P10828 1/20 0.32
HIF1A Q16665 1/20 0.32
TYMP P19971 1/20 0.32
HPRT1 P00492 1/20 0.32
PNP P00491 1/20 0.32
SLC28A2 O43868 1/20 0.32
ADK P55263 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9851819 0.92 ALDH1A1 (0.42) ALDH1A1MAPTMEN1KMT2AATG7
SCHEMBL9851790 0.92 ALDH1A1 (0.42) ALDH1A1MAPTMEN1KMT2AATG7
SCHEMBL9851811 0.89 ALDH1A1 (0.40) ALDH1A1MAPTMEN1KMT2AATG7
SCHEMBL9851884 0.84 ATG7 (0.43) ALDH1A1MAPTMEN1KMT2AATG7
SCHEMBL9851859 0.83 ALDH1A1 (0.39) ALDH1A1MAPTMEN1KMT2AATG7
SCHEMBL9851728 0.82 ATG7 (0.43) ALDH1A1MAPTMEN1KMT2AATG7
SCHEMBL6912032 0.82 ALDH1A1 (0.55) ALDH1A1MAPTMEN1KMT2AATG7
SCHEMBL1144829 0.82 ALDH1A1 (0.55) ALDH1A1MAPTMEN1KMT2AATG7
SCHEMBL6912039 0.82 ALDH1A1 (0.55) ALDH1A1MAPTMEN1KMT2AATG7
SCHEMBL9851722 0.81 MAPT (0.47) ALDH1A1MAPTMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450102-A1 NUCLEOSIDE DERIVATIVE Yamasa Shoyu Kabushiki Kaisha (JP) 1991-10-09 EP disclosed