Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | TK2 | O00142 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851916 | 1.00 | LPAR1 (0.36) | LPAR1LPAR3NLRP3NT5ESTING1 | |
| SCHEMBL9851863 | 1.00 | LPAR1 (0.36) | LPAR1LPAR3NLRP3NT5ESTING1 | |
| SCHEMBL9851865 | 0.90 | PRKCA (0.37) | LPAR1LPAR3NLRP3TK2 | |
| SCHEMBL9851795 | 0.90 | PRKCA (0.37) | LPAR1LPAR3NLRP3TK2 | |
| SCHEMBL9851715 | 0.84 | ATG7 (0.44) | NT5E | |
| SCHEMBL9851807 | 0.84 | ATG7 (0.44) | NT5E | |
| SCHEMBL9851698 | 0.82 | PRKCA (0.42) | STING1ALDH1A1TK2 | |
| SCHEMBL9851764 | 0.82 | PRKCA (0.42) | STING1ALDH1A1TK2 | |
| SCHEMBL9851850 | 0.82 | TK2 (0.42) | TK2 | |
| SCHEMBL9851753 | 0.82 | TK2 (0.46) | TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450102-A1 | NUCLEOSIDE DERIVATIVE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1991-10-09 | — | — | EP | disclosed |