SCHEMBL9851785

SCHEMBL9851785

C[Si](C)(C)OC[C@@H]1C[C@@H](O)[C@H](n2cnc3c(O)ncnc32)O1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.45
ADORA3 P0DMS8 5/20 0.45
SLC29A1 Q99808 1/20 0.44
HIF1A Q16665 1/20 0.40
ADORA2B P29275 1/20 0.39
NT5E P21589 1/20 0.39
AHCY P23526 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9851797 1.00 BCHE (0.45) BCHEADORA3SLC29A1HIF1AADORA2B
SCHEMBL9851774 0.89 BCHE (0.43) BCHEADORA3SLC29A1HIF1ANT5E
SCHEMBL9851784 0.89 BCHE (0.43) BCHEADORA3SLC29A1HIF1ANT5E
SCHEMBL9851713 0.87 SLC29A1 (0.44) BCHEADORA3SLC29A1HIF1AADORA2B
SCHEMBL646509 0.87 BCHE (0.46) BCHEADORA3SLC29A1ADORA2BNT5E
SCHEMBL9851706 0.87 SLC29A1 (0.44) BCHEADORA3SLC29A1HIF1AADORA2B
SCHEMBL9851727 0.87 ADORA3 (0.37) BCHEADORA3AHCY
SCHEMBL98800 0.86 SLC29A1 (0.56) ADORA3SLC29A1HIF1AADORA2B
SCHEMBL98801 0.86 SLC29A1 (0.56) ADORA3SLC29A1HIF1AADORA2B
SCHEMBL9851740 0.85 BCHE (0.41) BCHEADORA3SLC29A1NT5EAHCY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450102-A1 NUCLEOSIDE DERIVATIVE Yamasa Shoyu Kabushiki Kaisha (JP) 1991-10-09 EP disclosed