SCHEMBL9851740

SCHEMBL9851740

CCCC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](O)[C@H](n2cnc3c(O)ncnc32)O1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.41
ADORA3 P0DMS8 3/20 0.39
SLC29A1 Q99808 1/20 0.39
AHCY P23526 1/20 0.36
EHMT1 Q9H9B1 1/20 0.36
NT5E P21589 1/20 0.36
ADORA1 P30542 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9851774 0.89 BCHE (0.43) BCHEADORA3SLC29A1NT5EADORA1
SCHEMBL9851784 0.89 BCHE (0.43) BCHEADORA3SLC29A1NT5EADORA1
SCHEMBL9851844 0.89 ADORA3 (0.35) ADORA3AHCYEHMT1ADORA1
SCHEMBL9851785 0.85 BCHE (0.45) BCHEADORA3SLC29A1AHCYNT5E
SCHEMBL9851797 0.85 BCHE (0.45) BCHEADORA3SLC29A1AHCYNT5E
SCHEMBL9851729 0.82 AHCY (0.35) AHCY
SCHEMBL646509 0.82 BCHE (0.46) BCHEADORA3SLC29A1AHCYNT5E
SCHEMBL9851699 0.80 GAA (0.38) SLC29A1AHCYADORA1
SCHEMBL9851825 0.80 EHMT1 (0.44) BCHEADORA3SLC29A1AHCYEHMT1
SCHEMBL9851835 0.80 EHMT1 (0.44) BCHEADORA3SLC29A1AHCYEHMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450102-A1 NUCLEOSIDE DERIVATIVE Yamasa Shoyu Kabushiki Kaisha (JP) 1991-10-09 EP disclosed