Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851793 | 0.91 | ALDH1A1 (0.37) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL9851764 | 0.87 | PRKCA (0.42) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL9851757 | 0.85 | ALDH1A1 (0.40) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL9851837 | 0.83 | ALDH1A1 (0.35) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL9851855 | 0.82 | NT5E (0.37) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL9851714 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL9851795 | 0.80 | PRKCA (0.37) | — | |
| SCHEMBL9851821 | 0.77 | ALDH1A1 (0.37) | ALDH1A1LMNASTING1HTTMAPT | |
| SCHEMBL9851863 | 0.76 | LPAR1 (0.36) | ALDH1A1STING1 | |
| SCHEMBL9851703 | 0.74 | MAPT (0.44) | ALDH1A1LMNASTING1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450102-A1 | NUCLEOSIDE DERIVATIVE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1991-10-09 | — | — | EP | disclosed |