Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | LTA4H | P09960 | 2/20 | 0.65 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491062 | 1.00 | LSS (0.68) | LSSKDM4EALDH1A1LTA4HKCNA3 | |
| SCHEMBL9851880 | 1.00 | LSS (0.68) | LSSKDM4EALDH1A1LTA4HKCNA3 | |
| SCHEMBL9851895 | 1.00 | LSS (0.68) | LSSKDM4EALDH1A1LTA4HKCNA3 | |
| SCHEMBL9851879 | 0.98 | LSS (0.70) | LSSKDM4EALDH1A1LTA4HKCNA3 | |
| SCHEMBL4632841 | 0.92 | LSS (0.79) | LSSKDM4EALDH1A1LTA4HKCNA3 | |
| Ethylamine SCHEMBL9872082 | 0.91 | KDM4E (0.66) | LSSKDM4EALDH1A1LTA4HKCNA3 | |
| SCHEMBL10678430 | 0.89 | LSS (0.87) | LSSKDM4EALDH1A1LTA4HSMN1; SMN2 | |
| SCHEMBL10683734 | 0.89 | LSS (0.87) | LSSKDM4EALDH1A1LTA4HSMN1; SMN2 | |
| SCHEMBL10682570 | 0.89 | LSS (0.87) | LSSKDM4EALDH1A1LTA4HSMN1; SMN2 | |
| SCHEMBL10682555 | 0.89 | LSS (0.87) | LSSKDM4EALDH1A1LTA4HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410359-A1 | Substituted aminoalkoxy-benzene-derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | disclosed |