SCHEMBL4632841

SCHEMBL4632841

CN(C)CCCOc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LSS P48449 1/20 0.79
LTA4H P09960 2/20 0.69
KDM4E B2RXH2 5/20 0.68
ALDH1A1 P00352 4/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
HRH3 Q9Y5N1 2/20 0.63
KCNA3 P22001 1/20 0.62
CACNA1B Q00975 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL27703437 0.96 LSS (0.73) LSSLTA4HKDM4EALDH1A1SMN1; SMN2
SCHEMBL9851879 0.94 LSS (0.70) LSSLTA4HKDM4EALDH1A1SMN1; SMN2
Ethylamine SCHEMBL9873135 0.92 LSS (0.69) LSSLTA4HKDM4EALDH1A1SMN1; SMN2
SCHEMBL13886633 0.92 LTA4H (0.83) LSSLTA4HKDM4EALDH1A1SMN1; SMN2
SCHEMBL9851898 0.92 LSS (0.68) LSSLTA4HKDM4EALDH1A1SMN1; SMN2
SCHEMBL9491062 0.92 LSS (0.68) LSSLTA4HKDM4EALDH1A1SMN1; SMN2
SCHEMBL9851880 0.92 LSS (0.68) LSSLTA4HKDM4EALDH1A1SMN1; SMN2
SCHEMBL9851895 0.92 LSS (0.68) LSSLTA4HKDM4EALDH1A1SMN1; SMN2
SCHEMBL1405661 0.89 LTA4H (0.85) LSSLTA4HKDM4EALDH1A1HRH3
SCHEMBL9671156 0.89 KDM4E (0.83) LSSLTA4HKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115318256-A Anion exchange-hydrophobic mixed mode chromatography resin 生物辐射实验室股份有限公司 2022-11-11 CN claimed
CN-111818980-B Anion exchange-hydrophobic mixed mode chromatography resins 生物辐射实验室股份有限公司 2022-10-11 CN claimed
EP-1924553-A1 BICYCLO[2.2.]HEPT-7-YLAMINE DERIVATIVES AND THEIR USES Argenta Discovery Limited (GB) 2008-05-28 EP claimed
CN-100383138-C N-monoacetyl o-phenylenediamines, their fused heterocyclic derivatives and their use as medicaments HOFFMANN LA ROCHE (CH) 2008-04-23 CN claimed
WO-2007017670-A1 BICYCLO[2.2.]HEPT-7-YLAMINE DERIVATIVES AND THEIR USES ARGENTA DISCOVERY LTD. (GB) 2007-02-15 WO claimed
CN-1747948-A Novel n-monoacylated o-phenylenediamines, their condensed heterocyclic derivatives and their use as pharmaceutical agents HOFFMANN LA ROCHE (CH) 2006-03-15 CN claimed
US-12583818-B2 Compound, preparation method thereof, and use thereof DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) 2026-03-24 US disclosed
US-12343702-B2 Anionic exchange-hydrophobic mixed mode chromatography resin BIO-RAD LABORATORIES, INC. (US) 2025-07-01 US disclosed
US-20250196100-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESIN BIO-RAD LABORATORIES, INC. 2025-06-19 US disclosed
CN-114981241-B Novel compounds, process for their preparation and their use 大邱庆北尖端医疗产业振兴财团 2024-11-19 CN disclosed
US-20230142654-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF PIMEDBIO, INC. (KR) 2023-05-11 US disclosed
US-20230142654-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF PIMEDBIO, INC. (KR) 2023-05-11 US disclosed
US-20230142654-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF PIMEDBIO, INC. (KR) 2023-05-11 US disclosed
CN-1304380-C Benzo[a]henazin-11-carboxamide derivatives and their use as joint inhibitors of topomerase I and II XENOVA LTD (GB) 2007-03-14 CN disclosed
US-7183409-B2 Basic mono- and bisazo compounds CLARIANT FINANCE (BVI) LIMITED (VG) 2007-02-27 US disclosed
US-7183409-B2 Basic mono- and bisazo compounds CLARIANT FINANCE (BVI) LIMITED (VG) 2007-02-27 US disclosed
WO-2007017670-A1 BICYCLO[2.2.]HEPT-7-YLAMINE DERIVATIVES AND THEIR USES ARGENTA DISCOVERY LTD. (GB) 2007-02-15 WO disclosed
CN-1747948-A Novel n-monoacylated o-phenylenediamines, their condensed heterocyclic derivatives and their use as pharmaceutical agents HOFFMANN LA ROCHE (CH) 2006-03-15 CN disclosed
CN-1433406-A Benzo [ a ] phenazine-11-amide derivatives and their use as combined topoisomerase I and II inhibitors XENOVA LTD (GB) 2003-07-30 CN disclosed
US-5021429-A Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers ALLEN & HANSBURYS LIMITED (GB) 1991-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583818-B2 Compound, preparation method thereof, and use thereof TYRO3, TH, SRMS LSS 744/4885LTA4H 1459/4885KDM4E 2818/4885
US-20230142654-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF TYR, TYRO3, TH LSS 1325/4885LTA4H 930/4885KDM4E 619/4885
US-20250196100-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESIN SLC7A1, ABCG2, MSR1 LSS 4236/4885LTA4H 1282/4885KDM4E 3608/4885
US-12343702-B2 Anionic exchange-hydrophobic mixed mode chromatography resin FCGRT, PBRM1, BCR LSS 4841/4885LTA4H 3846/4885KDM4E 1451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.