Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | LSS | P48449 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PDE1A | P54750 | 1/20 | 0.52 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.52 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylamine SCHEMBL9873135 | 0.95 | LSS (0.69) | KDM4EALDH1A1LSSLTA4HSMN1; SMN2 | |
| SCHEMBL9851879 | 0.93 | LSS (0.70) | KDM4EALDH1A1LSSLTA4HSMN1; SMN2 | |
| SCHEMBL9851895 | 0.91 | LSS (0.68) | KDM4EALDH1A1LSSLTA4HSMN1; SMN2 | |
| SCHEMBL9851898 | 0.91 | LSS (0.68) | KDM4EALDH1A1LSSLTA4HSMN1; SMN2 | |
| SCHEMBL9491062 | 0.91 | LSS (0.68) | KDM4EALDH1A1LSSLTA4HSMN1; SMN2 | |
| SCHEMBL9851880 | 0.91 | LSS (0.68) | KDM4EALDH1A1LSSLTA4HSMN1; SMN2 | |
| Ethylamine SCHEMBL9871196 | 0.89 | LTA4H (0.73) | KDM4EALDH1A1LSSLTA4HSMN1; SMN2 | |
| Methylamine SCHEMBL27703437 | 0.87 | LSS (0.73) | KDM4EALDH1A1LSSLTA4HSMN1; SMN2 | |
| SCHEMBL4632841 | 0.87 | LSS (0.79) | KDM4EALDH1A1LSSLTA4HSMN1; SMN2 | |
| SCHEMBL10678545 | 0.82 | LSS (0.90) | KDM4EALDH1A1LSSLTA4HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |