Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 16/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646362 | 0.81 | TDP1 (0.39) | IRAK4TSHRPPARGTDP1NR2E3 | |
| SCHEMBL21565414 | 0.78 | GAA (0.41) | IRAK4 | |
| SCHEMBL21565344 | 0.78 | GAA (0.41) | IRAK4 | |
| SCHEMBL21565345 | 0.78 | GAA (0.41) | IRAK4 | |
| Hydrochloric Acid SCHEMBL8476980 | 0.78 | PDK2 (0.39) | IRAK4IRAK1MAPT | |
| SCHEMBL5215591 | 0.76 | IRAK4 (0.37) | IRAK4IRAK1 | |
| SCHEMBL9865629 | 0.76 | IRAK4 (0.37) | IRAK4IRAK1 | |
| SCHEMBL21180014 | 0.74 | IRAK4 (0.39) | IRAK4IRAK1 | |
| SCHEMBL15727499 | 0.74 | IRAK4 (0.39) | IRAK4IRAK1 | |
| SCHEMBL12409742 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438311-A2 | Di- and tripeptide renin inhibitors | MERCK & CO. INC. (US) | 1991-07-24 | — | — | EP | disclosed |