Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | DAO | P14920 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636643 | 0.82 | HSD17B10 (0.70) | GAAHSD17B10ALDH1A1KDM4ERAB9A | |
| SCHEMBL14355126 | 0.72 | GAA (0.57) | GAARAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL4212367 | 0.72 | GAA (0.56) | GAAHSD17B10ALDH1A1KDM4ERAB9A | |
| SCHEMBL11508561 | 0.70 | GAA (0.54) | GAAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14355130 | 0.69 | GAA (0.53) | GAAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14355173 | 0.68 | LMNA (0.55) | GAAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15928188 | 0.68 | POLB (0.55) | GAAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL12242700 | 0.67 | — | — | |
| SCHEMBL5106178 | 0.67 | MAPK1 (1.00) | GAAHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL83796 | 0.66 | MEN1 (0.80) | GAAALDH1A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422369-A2 | Substituted carbamoyltriazoles | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |