SCHEMBL9852018

SCHEMBL9852018

NC(=O)C[C@H](N)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.53
MME P08473 6/20 0.46
ECE1 P42892 2/20 0.45
PDCD1LG2 Q9BQ51 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
CA2 P00918 3/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9852015 1.00 TGFBR1 (0.53) TGFBR1MMEECE1PDCD1LG2CD274
SCHEMBL29826167 0.96 TGFBR1 (0.50) TGFBR1MMEECE1PDCD1LG2CD274
SCHEMBL30390247 0.95 TGFBR1 (0.49) TGFBR1MMEECE1PDCD1LG2CD274
SCHEMBL30010888 0.93 TGFBR1 (0.47) TGFBR1MMEECE1PDCD1LG2CD274
SCHEMBL30389257 0.92 MME (0.48) TGFBR1MMEECE1PDCD1LG2CD274
SCHEMBL29517650 0.92 MME (0.48) TGFBR1MMEECE1PDCD1LG2CD274
SCHEMBL30010357 0.91 ECE1 (0.49) TGFBR1MMEECE1PDCD1LG2CD274
SCHEMBL29963242 0.91 MME (0.46) TGFBR1MMEECE1PDCD1LG2CD274
SCHEMBL29867829 0.91 MME (0.47) TGFBR1MMEECE1PDCD1LG2CD274
SCHEMBL18075525 0.89 ECE1 (0.56) TGFBR1ECE1PDCD1LG2CD274CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025038031-A1 ENGINEERED MITOCHONDRION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2025-02-20 WO claimed
US-20220289846-A1 ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 ZYDUS LIFESCIENCES LIMITED (IN) 2022-09-15 US claimed
EP-3997126-A1 ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 Cadila Healthcare Limited (IN) 2022-05-18 EP claimed
CN-114127317-A Method of diagnosing disease 4D制药科克有限公司 2022-03-01 CN claimed
CN-114032271-A Oyster polypeptide and polypeptide powder with uric acid reducing effect as well as preparation method and application of oyster polypeptide and polypeptide powder 浙江工业大学 2022-02-11 CN claimed
EP-0457314-A1 Nutrient compositions containing peptides CLINTEC NUTRITION COMPANY (US) 1991-11-21 EP claimed
WO-2026107097-A1 SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF ENLAZA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
EP-4713368-A1 ANTI-CD28 ANTIBODIES AND METHODS RELATED THERETO Adimab, LLC (US) 2026-03-25 EP disclosed
US-12576025-B2 Pharmaceutical parenteral composition of dual GLP1/2 agonist ZEALAND PHARMA A/S (DK) 2026-03-17 US disclosed
EP-4701651-A2 CORECEPTOR CHIMERIC ANTIGEN RECEPTOR Vanudis GmbH (DE) 2026-03-04 EP disclosed
EP-4702049-A1 NOVEL EGFR BINDING PROTEINS Universität Stuttgart (DE) 2026-03-04 EP disclosed
US-12534529-B1 PTK7-binding proteins SOLVE THERAPEUTICS, INC. (US) 2026-01-27 US disclosed
US-20260008868-A1 5T4-BINDING PROTEINS SOLVE THERAPEUTICS, INC. (US) 2026-01-08 US disclosed
EP-3982919-A1 PHARMACEUTICAL PARENTERAL COMPOSITION OF DUAL GLP1/2 AGONIST Zealand Pharma A/S (DK) 2022-04-20 EP disclosed
CN-111620948-B Antibodies to IL-33 南京赛新生物科技有限公司 2022-04-08 CN disclosed
CN-114207728-A Prediction of side chain degradation in polymers by physics-based simulations 杰南技术公司 2022-03-18 CN disclosed
US-11248209-B2 Mature dendritic cell compositions and methods for culturing same COIMMUNE, INC. (US) 2022-02-15 US disclosed
CN-114032271-A Oyster polypeptide and polypeptide powder with uric acid reducing effect as well as preparation method and application of oyster polypeptide and polypeptide powder 浙江工业大学 2022-02-11 CN disclosed
CN-113966226-A Pharmaceutical parenteral compositions of dual GLP1/2 agonists 西兰制药公司 2022-01-21 CN disclosed
CN-113966225-A Pharmaceutical parenteral compositions of dual GLP1/2 agonists 西兰制药公司 2022-01-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11248209-B2 Mature dendritic cell compositions and methods for culturing same CD40, CD40LG, CCR7 TGFBR1 229/4885MME 3318/4885ECE1 3217/4885
US-12576025-B2 Pharmaceutical parenteral composition of dual GLP1/2 agonist SLC5A2, GLP1R, SLC5A11 TGFBR1 3093/4885MME 2515/4885ECE1 2482/4885
US-12534529-B1 PTK7-binding proteins ROR1, FZD7, LTK TGFBR1 184/4885MME 4292/4885ECE1 4644/4885
US-20260008868-A1 5T4-BINDING PROTEINS TNFSF11, TMIGD3, CTNNBL1 TGFBR1 40/4885MME 1427/4885ECE1 3212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.