Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011182 | 0.78 | NPC1 (0.70) | KMT2AMEN1ALDH1A1DRD4MCHR1 | |
| SCHEMBL9872559 | 0.78 | DRD4 (0.78) | KMT2AMEN1ACHEDRD4MCHR1 | |
| SCHEMBL9872534 | 0.76 | DRD4 (0.64) | KMT2AMEN1ALDH1A1DRD4MCHR1 | |
| SCHEMBL2536771 | 0.75 | NPC1 (0.64) | KMT2AMEN1SMN1; SMN2GRM5NPC1 | |
| SCHEMBL26633947 | 0.74 | NPC1 (0.60) | KMT2AMEN1ALDH1A1MCHR1SMN1; SMN2 | |
| SCHEMBL9773084 | 0.74 | CXCR4 (0.68) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL11240479 | 0.71 | RAB9A (0.76) | KMT2AMEN1ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL11813023 | 0.70 | HPGDS (0.62) | KMT2AMEN1SMN1; SMN2GRM5NPC1 | |
| SCHEMBL2230140 | 0.70 | NPC1 (0.79) | KMT2AMEN1ALDH1A1SMN1; SMN2GRM5 | |
| SCHEMBL124395 | 0.70 | NPC1 (0.79) | KMT2AMEN1ALDH1A1SMN1; SMN2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |
| US-5028616-A | Antiarrhythmia Agents | G. D. SEARLE & CO. (US) | 1991-07-02 | — | — | US | disclosed |