Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.66 |
| ▸ | CES1 | P23141 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25193128 | 0.87 | MAPT (0.57) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL27301045 | 0.85 | CES2 (0.64) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL27977334 | 0.84 | CES2 (0.67) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL626786 | 0.82 | AKR1C1 (0.57) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL11886125 | 0.82 | AKR1C1 (0.57) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL13718665 | 0.82 | AKR1C1 (0.57) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL5084327 | 0.81 | CES2 (0.62) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL527100 | 0.80 | NQO2 (0.71) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL10669156 | 0.80 | NQO2 (0.71) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL2156563 | 0.80 | CES2 (1.00) | CES2CES1MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | claimed |