SCHEMBL2156563

SCHEMBL2156563

COc1ccc(C(=O)C(=O)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 7/20 1.00
CES1 P23141 7/20 1.00
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
MAPT P10636 3/20 0.62
NPC1 O15118 4/20 0.62
RAB9A P51151 4/20 0.62
PAX8 Q06710 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
KDM4E B2RXH2 1/20 0.58
HPGD P15428 1/20 0.58
CDK5 Q00535 2/20 0.57
CDK5R1 Q15078 2/20 0.57
PKM P14618 1/20 0.57
KCNK9 Q9NPC2 1/20 0.57
PARP1 P09874 1/20 0.57
PARP10 Q53GL7 1/20 0.57
PARP2 Q9UGN5 1/20 0.57
PARP4 Q9UKK3 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL981452 0.98 CES2 (0.96) CES2CES1CA1CA2MAPT
Hydrochloric Acid SCHEMBL905770 0.98 CES2 (0.96) CES2CES1CA1CA2MAPT
Benzil SCHEMBL27611875 0.94 CES2 (0.89) CES2CES1CA1CA2MAPT
Benzoic Acid SCHEMBL29612332 0.94 CES2 (0.89) CES2CES1CA1CA2MAPT
SCHEMBL557152 0.91 CES2 (1.00) CES2CES1CA1CA2MAPT
SCHEMBL14507040 0.91 CES2 (1.00) CES2CES1CA1CA2MAPT
SCHEMBL7560411 0.90 CES2 (0.81) CES2CES1CA1CA2MAPT
SCHEMBL8652128 0.90 CES2 (0.81) CES2CES1CA1CA2MAPT
SCHEMBL30504863 0.89 CES2 (0.79) CES2CES1CA1CA2MAPT
SCHEMBL29548151 0.89 CES2 (0.95) CES2CES1CA1CA2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912606-A Catalyst suitable for ethylene polymerization reaction and preparation method and application thereof 中国石油化工股份有限公司 2025-05-02 CN claimed
CN-118388891-A Thermoplastic cable insulation material and preparation method thereof 中国石油天然气股份有限公司 2024-07-26 CN claimed
US-12006296-B1 5-(4-methoxyphenyl)-1-hexyl-2-(4-nitrophenyl)-4-phenyl-1H-imidazoleas an antimicrobial compound King Faisal University (SA) 2024-06-11 US claimed
US-11970461-B1 1-hexyl-5-(4-methoxyphenyl)-2,4-diphenyl-1H-imidazole as an antimicrobial compound King Faisal University (SA) 2024-04-30 US claimed
US-7973034-B2 Ameliorating toxic effects of such as cancer therapy drugs or addictive drug overdose ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2011-07-05 US claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
US-4135033-A HEAT DISSOCIABLE MOLECULAR COMPLEX BARRIER LAYER LAWTON WILLIAM R 1979-01-16 US claimed
CN-119912606-A Catalyst suitable for ethylene polymerization reaction and preparation method and application thereof 中国石油化工股份有限公司 2025-05-02 CN disclosed
CN-118388890-A Cable insulation material and preparation method thereof 中国石油天然气股份有限公司 2024-07-26 CN disclosed
CN-118388884-A Polypropylene composition and preparation method thereof, cable insulation layer and high-voltage cable 中国石油天然气股份有限公司 2024-07-26 CN disclosed
CN-118388883-A Propylene-based resin material, and preparation method and application thereof 中国石油天然气股份有限公司 2024-07-26 CN disclosed
CN-118388891-A Thermoplastic cable insulation material and preparation method thereof 中国石油天然气股份有限公司 2024-07-26 CN disclosed
US-12006296-B1 5-(4-methoxyphenyl)-1-hexyl-2-(4-nitrophenyl)-4-phenyl-1H-imidazoleas an antimicrobial compound King Faisal University (SA) 2024-06-11 US disclosed
EP-0101210-B1 ASSEMBLY FOR USE IN MAKING A PRINTING PLATE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-09-27 EP disclosed
EP-0255286-A2 Visible light-cured impression material Kerr Manufacturing Company (a Delaware corporation) (US) 1988-02-03 EP disclosed
EP-0101210-A2 Assembly for use in making a printing plate IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-02-22 EP disclosed
US-4135033-A HEAT DISSOCIABLE MOLECULAR COMPLEX BARRIER LAYER LAWTON WILLIAM R 1979-01-16 US disclosed
US-4087463-A COBALT CARBONYL CATALYST MONSANTO COMPANY (US) 1978-05-02 US disclosed
US-4009040-A DEPOLYMERIZATION TO FORM POSITIVE IMAGES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-02-22 US disclosed
US-4009022-A Selective antagonists for triazine herbicides ROHM AND HAAS COMPANY (US) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11970461-B1 1-hexyl-5-(4-methoxyphenyl)-2,4-diphenyl-1H-imidazole as an antimicrobial compound NOD2, DPP4, MIF CES2 4497/4885CES1 4521/4885CA1 4866/4885
US-12006296-B1 5-(4-methoxyphenyl)-1-hexyl-2-(4-nitrophenyl)-4-phenyl-1H-imidazoleas an antimicrobial compound TLR4, CASP4, UMPS CES2 3894/4885CES1 3911/4885CA1 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.