Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977053 | 0.91 | ALDH1A1 (0.51) | LMNAMAPTABCG2NPC1RAB9A | |
| SCHEMBL9852379 | 0.81 | MCL1 (0.54) | LMNAMAPTRECQLATML3MBTL1 | |
| SCHEMBL14104052 | 0.78 | ALDH1A1 (0.68) | MAPTATMALDH1A1HPGDCYP1A2 | |
| SCHEMBL13412689 | 0.78 | ALDH1A1 (0.68) | MAPTATMALDH1A1HPGDCYP1A2 | |
| SCHEMBL9246430 | 0.75 | LMNA (0.59) | LMNAMAPTABCG2NPC1RAB9A | |
| SCHEMBL1893666 | 0.75 | ABCG2 (0.53) | LMNAMAPTABCG2NPC1RAB9A | |
| SCHEMBL1893667 | 0.75 | ABCG2 (0.53) | LMNAMAPTABCG2NPC1RAB9A | |
| SCHEMBL1893669 | 0.75 | ABCG2 (0.53) | LMNAMAPTABCG2NPC1RAB9A | |
| SCHEMBL8976994 | 0.74 | ALDH1A1 (0.55) | LMNAMAPTRAB9ARECQLATM | |
| SCHEMBL8976998 | 0.74 | ALDH1A1 (0.55) | LMNAMAPTRAB9ARECQLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | claimed |
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |