Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977055 | 0.86 | MIF (0.56) | KMT2AKDM4ELMNACES2CES1 | |
| SCHEMBL9852384 | 0.82 | SENP1 (0.51) | KMT2AKDM4ELMNAPKMMEN1 | |
| SCHEMBL14104052 | 0.80 | ALDH1A1 (0.68) | KMT2AKDM4EPKMCES2CES1 | |
| SCHEMBL13412689 | 0.80 | ALDH1A1 (0.68) | KMT2AKDM4EPKMCES2CES1 | |
| SCHEMBL8965376 | 0.78 | ALDH1A1 (0.55) | KMT2AKDM4ELMNAPKMMEN1 | |
| SCHEMBL8976994 | 0.78 | ALDH1A1 (0.55) | KMT2AKDM4ELMNAPKMMEN1 | |
| SCHEMBL8976998 | 0.78 | ALDH1A1 (0.55) | KMT2AKDM4ELMNAPKMMEN1 | |
| SCHEMBL6883491 | 0.77 | ADORA2A (0.66) | KMT2AKDM4ELMNAPKMMEN1 | |
| SCHEMBL9800315 | 0.77 | ADORA2A (0.66) | KMT2AKDM4ELMNAPKMMEN1 | |
| SCHEMBL14103907 | 0.76 | EGFR (0.64) | KMT2AKDM4ELMNAPKMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | claimed |
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |