Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634417 | 0.84 | SMN1; SMN2 (0.32) | SMN1; SMN2CYP3A4GAA | |
| SCHEMBL28115632 | 0.79 | MAPK1 (0.38) | SMN1; SMN2CYP3A4CYP1A2ALDH1A1KMT2A | |
| SCHEMBL3042385 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL2224518 | 0.74 | USP2 (0.47) | SMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL12144120 | 0.73 | HRH3 (0.38) | LMNAALDH1A1 | |
| SCHEMBL7261429 | 0.72 | — | — | |
| SCHEMBL18478526 | 0.71 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP3A4GAALMNAALDH1A1 | |
| SCHEMBL11310663 | 0.70 | — | — | |
| SCHEMBL26667566 | 0.70 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL11355212 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423705-A2 | Process for the stereochemical inversion of (2S,3S)-2-amino-3-phenyl-1,3-propanediols into their (2R,3R) enantiomers | ZAMBON GROUP S.p.A. (IT) | 1991-04-24 | — | — | EP | disclosed |