SCHEMBL2224518

SCHEMBL2224518

CC(C)(C)OC(=O)N1CCOC1(C)C

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
RECQL P46063 1/20 0.39
SPHK1 Q9NYA1 1/20 0.38
CTSK P43235 1/20 0.36
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
HPGD P15428 1/20 0.34
EPHX2 P34913 1/20 0.34
HCRTR2 O43614 1/20 0.34
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
BUB1 O43683 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19088593 0.85 USP2 (0.33) USP2SMN1; SMN2SPHK1
SCHEMBL28115632 0.79 MAPK1 (0.38) USP2SMN1; SMN2RECQLALDH1A1MAPT
SCHEMBL28282841 0.78 TSHR (0.47) SMN1; SMN2RECQLHPGDALDH1A1LMNA
SCHEMBL31197138 0.76 USP2 (0.53) USP2SMN1; SMN2RECQLCTSKCHRM2
SCHEMBL9852425 0.74 SMN1; SMN2 (0.38) SMN1; SMN2HPGDALDH1A1LMNA
SCHEMBL26884952 0.72 USP2 (0.42) USP2SMN1; SMN2RECQLCTSKCHRM2
SCHEMBL2634417 0.72 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL16838402 0.72 USP2 (0.57) USP2SMN1; SMN2RECQLHPGDEPHX2
SCHEMBL31105190 0.72 USP2 (0.49) USP2SMN1; SMN2RECQLCTSKCHRM2
SCHEMBL16413908 0.72 USP2 (0.49) USP2SMN1; SMN2RECQLCTSKCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118541362-A Pyridazinylamino derivatives as ALK5 inhibitors 奇斯药制品公司 2024-08-23 CN claimed
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 US disclosed
US-20250100997-A1 PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2025-03-27 US disclosed
US-12246081-B2 Deodorant compositions CONOPCO, INC. (US) 2025-03-11 US disclosed
CN-119192008-A Preparation method of L-vinylglycine hydrochloride 上海海皋科技有限公司 2024-12-27 CN disclosed
CN-119192008-A Preparation method of L-vinylglycine hydrochloride 上海海皋科技有限公司 2024-12-27 CN disclosed
EP-4463448-A1 PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2024-11-20 EP disclosed
CN-118878461-A PD-1/PD-L1 inhibitors 吉利德科学公司 2024-11-01 CN disclosed
CN-118541362-A Pyridazinylamino derivatives as ALK5 inhibitors 奇斯药制品公司 2024-08-23 CN disclosed
CN-118159548-A Antiviral compounds 安力高医药股份有限公司 2024-06-07 CN disclosed
US-20080255182-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INC. 2008-10-16 US disclosed
EP-1577301-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 EP disclosed
CN-1561332-A Preparation of HIV protease inhibitors HOFFMANN LA ROCHE (CH) 2005-01-05 CN disclosed
EP-1404664-A1 AMINEDIOLS FOR THE TREATMENT OF ALZHEIMER'S DISEASE Elan Pharmaceuticals, Inc. (US) 2004-04-07 EP disclosed
WO-2003006453-A1 AMINEDIOLS FOR THE TREATMENT OF ALZHEIMER'S DISEASE ELAN PHARMACEUTICALS, INC. (US) 2003-01-23 WO disclosed
CN-1379762-A Beta substituted metalloprotease inhibitors PROCTER & GAMBLE (US) 2002-11-13 CN disclosed
EP-1140849-A1 AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-10-10 EP disclosed
EP-1073672-A1 ANTIPICORNAVIRAL COMPOUNDS, THEIR PREPARATION AND USE AGOURON PHARMACEUTICALS, INC. (US) 2001-02-07 EP disclosed
WO-2000040560-A1 AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-07-13 WO disclosed
WO-1999057135-A1 ANTIPICORNAVIRAL COMPOUNDS, THEIR PREPARATION AND USE AGOURON PHARMACEUTICALS, INC. (US) 1999-11-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS KLK3, BRDT, BPHL USP2 755/4885SMN1; SMN2 3766/4885RECQL 3973/4885
US-12246081-B2 Deodorant compositions DHODH, STS, DDT USP2 541/4885SMN1; SMN2 3650/4885RECQL 1200/4885
US-20080255182-A1 Certain chemical entities, compositions, and methods KIF5B, KIF2C, PLK1 USP2 2468/4885SMN1; SMN2 1149/4885RECQL 139/4885
US-20250100997-A1 PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS ALK, TGFBR1, ACVR1 USP2 3820/4885SMN1; SMN2 3267/4885RECQL 4832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.