Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224518 | 0.79 | USP2 (0.47) | SMN1; SMN2ALDH1A1MAPTUSP2RECQL | |
| SCHEMBL9852425 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL2634417 | 0.77 | SMN1; SMN2 (0.32) | SMN1; SMN2CYP3A4 | |
| SCHEMBL8915143 | 0.71 | — | — | |
| SCHEMBL1666023 | 0.70 | MEN1 (0.55) | SMN1; SMN2KMT2AALDH1A1MEN1HTT | |
| SCHEMBL9800446 | 0.70 | CTSK (0.31) | SMN1; SMN2 | |
| SCHEMBL22167671 | 0.68 | USP2 (0.45) | MAPK1KMT2AALDH1A1CYP3A4MAPT | |
| SCHEMBL12144120 | 0.67 | HRH3 (0.38) | MAPK1ALDH1A1 | |
| SCHEMBL31674298 | 0.66 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2AALDH1A1CYP3A4MEN1 | |
| SCHEMBL15116477 | 0.65 | USP2 (0.39) | MAPK1KMT2AALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132968-B | Bromodomain-inhibiting compound for preventing or treating cancer and pharmaceutical composition containing the same | 康佳诺医疗科技发展有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-106132968-A | Bromodomain-inhibiting compound for preventing or treating cancer and pharmaceutical composition containing the same | 康佳诺医疗科技发展有限公司 | 2016-11-16 | — | — | CN | disclosed |