Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 4/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915503 | 0.75 | CYP1A2 (0.42) | KDM4EALDH1A1TDP1LMNAGAA | |
| SCHEMBL1704134 | 0.72 | — | — | |
| SCHEMBL7908960 | 0.70 | HTR1B (0.69) | HTR1BHTR1DKDM4EALDH1A1TDP1 | |
| SCHEMBL14075752 | 0.66 | KDM4E (0.43) | HTR1BHTR1DKDM4EALDH1A1TDP1 | |
| SCHEMBL21776313 | 0.65 | HRH1 (0.63) | HTR1BHTR1DKDM4EALDH1A1TDP1 | |
| SCHEMBL6110598 | 0.65 | L3MBTL4 (0.57) | HTR1BHTR1DKDM4EALDH1A1TDP1 | |
| SCHEMBL12951415 | 0.65 | MAPT (0.43) | HTR1BHTR1DKDM4EALDH1A1TDP1 | |
| SCHEMBL23067907 | 0.64 | HTR1B (0.49) | HTR1BHTR1DKDM4EHRH1SLC6A4 | |
| SCHEMBL21595770 | 0.64 | MAPT (0.56) | KDM4EALDH1A1TDP1LMNAL3MBTL1 | |
| SCHEMBL21601457 | 0.64 | HTR1B (0.49) | HTR1BHTR1DKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413343-A2 | Furan derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-20 | — | — | EP | disclosed |