Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872720 | 0.80 | KDM4E (0.36) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL9852576 | 0.79 | KDM4E (0.34) | KDM4EPKM | |
| SCHEMBL9627220 | 0.70 | NPSR1 (0.45) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL9749147 | 0.70 | MAPK1 (0.40) | HPGDHSD17B10ALDH1A1MAPTALOX15 | |
| SCHEMBL9852546 | 0.68 | PTGS1 (0.36) | HPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL13969630 | 0.65 | KDM4E (0.35) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL2636627 | 0.64 | KDM4E (0.34) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL4760779 | 0.63 | KDM4E (0.33) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL4632562 | 0.63 | PRKCI (0.38) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL15737336 | 0.63 | KDM4E (0.41) | KDM4EHPGDHSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409055-A1 | Cephalosporin derivatives and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-23 | — | — | EP | disclosed |