Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852546 | 0.86 | PTGS1 (0.36) | MAPK1HSD17B10MAPTTSHRKMT2A | |
| SCHEMBL9748133 | 0.85 | HSD17B10 (0.32) | MAPK1HSD17B10MAPTHPGDALDH1A1 | |
| SCHEMBL10688854 | 0.77 | HSD17B10 (0.43) | MAPK1HSD17B10TP53MAPTTSHR | |
| SCHEMBL9748003 | 0.75 | PTGS1 (0.36) | MAPK1HSD17B10MAPTTSHRKMT2A | |
| SCHEMBL9749314 | 0.73 | HSD17B10 (0.40) | HSD17B10KMT2AHPGDFFAR1ALDH1A1 | |
| SCHEMBL10872720 | 0.72 | KDM4E (0.36) | HSD17B10MAPTHPGDALDH1A1ALOX15 | |
| SCHEMBL9852497 | 0.70 | KDM4E (0.34) | HSD17B10MAPTHPGDALDH1A1ALOX15 | |
| SCHEMBL846103 | 0.66 | MAPT (0.46) | MAPK1HSD17B10MAPTKMT2AHPGD | |
| SCHEMBL10872710 | 0.64 | KMT2A (0.43) | MAPK1HSD17B10TP53MAPTTSHR | |
| SCHEMBL10118118 | 0.63 | ALDH1A1 (0.53) | MAPK1HSD17B10TSHRKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |