Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PPOX | P50336 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788466 | 0.86 | TDP1 (0.66) | TDP1TTRMEN1KMT2APPOX | |
| SCHEMBL3304697 | 0.86 | TDP1 (0.56) | TDP1TTRMEN1KMT2APPOX | |
| SCHEMBL11264191 | 0.85 | TDP1 (0.46) | TDP1TTRMEN1KMT2APPOX | |
| SCHEMBL11263520 | 0.85 | TDP1 (0.46) | TDP1TTRMEN1KMT2APPOX | |
| SCHEMBL11263525 | 0.85 | TDP1 (0.46) | TDP1TTRMEN1KMT2APPOX | |
| SCHEMBL8993430 | 0.78 | PKM (0.37) | TDP1TTRMEN1KMT2APPOX | |
| SCHEMBL2730973 | 0.77 | TDP1 (0.76) | TDP1TTRMEN1KMT2APPOX | |
| SCHEMBL6421578 | 0.77 | TDP1 (0.56) | TDP1TTRMEN1KMT2APPOX | |
| SCHEMBL11263627 | 0.77 | TDP1 (0.57) | TDP1TTRMEN1KMT2APPOX | |
| SCHEMBL10499994 | 0.76 | MEN1 (0.64) | TDP1TTRMEN1KMT2APPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415212-A1 | Aryloxynaphthalene derivatives | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0391187-A2 | Substituted 4-amino-5-alkylthio-1,2,4-triazol-3-ones | BAYER AG (DE) | 1990-10-10 | — | — | EP | disclosed |